Tuberous sclerosis complex-associated kidney angiomyolipoma: from contemplation to action.
نویسنده
چکیده
2012-SAP029 ERA-EDTACongress 16. Balligand JL, Pirson Y, Squifflet JP et al. Outcome of patients with tuberous sclerosis after renal transplantation. Transplantation 1990; 49: 515–518 17. van Slegtenhorst M, de Hoogt R, Hermans C et al. Identification of the tuberous sclerosis gene TSC1 on chromosome 9q34. Science 1997; 277: 805–808 18. European Chromosome 16 Tuberous Sclerosis Consortium. Identification and characterization of the tuberous sclerosis gene on chromosome 16. Cell 1993; 75: 1305–1315 19. Kenerson HL, Aicher LD, True LD et al. Activated mammalian target of rapamycin pathway in the pathogenesis of tuberous sclerosis complex renal tumors. Cancer Res 2002; 62: 5645–5650 20. Lee L, Sudentas P, Donohue B et al. Efficacy of a rapamycin analog (CCI-779) and IFN-gamma in tuberous sclerosis mouse models. Genes Chromosomes Cancer 2005; 42: 213–227 21. Franz DN, Leonard J, Tudor C et al. Rapamycin causes regression of astrocytomas in tuberous sclerosis complex. Ann Neurol 2006; 59: 490–498 22. Wienecke R, Fackler I, Linsenmaier U et al. Antitumoral activity of rapamycin in renal angiomyolipoma associated with tuberous sclerosis complex. Am J Kidney Dis 2006; 48: e27–e29 23. Zonnenberg B, Budde K, Kingswood C et al. Angiomyolipoma response to everolimus treatement in patients with tuberous F U L L R E V IE W
منابع مشابه
Concurrent hepatic and ruptured renal angiomyolipoma in tuberous sclerosis complex.
Angiomyolipoma of the liver or kidney is one of the clinical manifestations of tuberous sclerosis complex. However, concurrence of angiomyolipoma in both liver and kidney associated with tuberous sclerosis complex is a rare entity. Renal angiomyolipomas with large aneurysms confer a higher probability of rupture as compared to small aneurysms. Herein, we document a case of tuberous sclerosis co...
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Here we report a case of 57-year-old woman with renal angiomyolipoma associated with tuberous sclerosis complex involving inferior vena cava thrombus. We could perform less invasive nephrectomy with thrombectomy because everolimus administration reduced the inferior vena cava thrombus. To the best of our knowledge, this is the first report the use of everolimus before performing surgery to trea...
متن کاملWunderlich's syndrome with hepatic angiomyolipoma in tuberous sclerosis.
We present a patient of tuberous sclerosis complex with bilateral renal angiomyolipoma and hepatic angiomyolipoma with spontaneous retroperitoneal hemorrhage from right angiomyolipoma (Wunderlich's syndrome). Nephron preserving approach was tried but the right kidney could not be salvaged. Hepatic angiomyolipoma was managed conservatively. Wunderlich's syndrome has been found in around 10% of c...
متن کاملReview of renal artery embolization for treatment of renal angiomyolipoma
Renal angiomyolipoma (AML) is a benign renal neoplasm with the exception of the rare epithelioid variant. AML may be sporadic or may be associated with tuberous sclerosis complex or pulmonary lymphangioleiomyomatosis. Risk of hemorrhage is the concern for patients with AML. Renal artery embolization (RAE) is the treatment of choice for acute hemorrhage from angiomyolipoma, and also firstline pr...
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ورودعنوان ژورنال:
- Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association
دوره 28 7 شماره
صفحات -
تاریخ انتشار 2013